Pharmacokinetics AUC Calculator
Determine total drug exposure ($AUC_{0-t}$) using the linear trapezoidal rule.
Ensure data is sorted chronologically by time.
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Non-Compartmental Analysis
The Area Under the Curve (AUC) is the definite integral of a drug's blood plasma concentration over time. It is a critical parameter for determining bioavailability, clearance, and bioequivalence.
Linear Trapezoidal Rule:
AUC = Σ [ 0.5 * (Cᵢ + Cᵢ₋₁) * (tᵢ - tᵢ₋₁) ]
AUC = Σ [ 0.5 * (Cᵢ + Cᵢ₋₁) * (tᵢ - tᵢ₋₁) ]