Gibbs Free Energy Calculator

Calculate thermodynamic spontaneity (ΔG) for metabolic and biochemical reactions.

Method A: ΔH & ΔS

Method B: Concentration (Q)

ΔG = ΔH - TΔS

Calculate standard free energy from enthalpy and entropy. The calculator automatically handles the standard J vs kJ mismatch.

Enthalpy Change (ΔH) kJ / mol

Entropy Change (ΔS) J / K·mol

Temperature (T) °C

Calculate actual free energy based on standard conditions and real-time cellular concentrations.

Standard Free Energy (ΔG°) kJ / mol

Reaction Quotient (Q) [Prod]/[React]

Temperature (T) °C

Gibbs Free Energy (ΔG)

0.00

kJ / mol

Equilibrium